HDL Cholesterol
Also written as: HDL-C, High-density lipoprotein
The cholesterol fraction that moves cholesterol away from arteries.
What it measures
The cholesterol carried on high-density lipoprotein particles, which transport cholesterol back to the liver.
Why a doctor orders it
Part of a standard lipid panel and used in cardiovascular risk calculators.
What is generally associated with a higher result
Higher HDL has historically been associated with lower cardiovascular risk at a population level, though research has complicated the picture, and very high values are not straightforwardly protective.
What is generally associated with a lower result
Lower HDL is associated at a population level with higher cardiovascular risk. It is influenced by genetics, physical inactivity, smoking, obesity, and some medications.
Everyday things that move this number
Not every shift in a value reflects disease. These are ordinary factors known to affect this particular measurement:
- Physical activity
- Alcohol
- Smoking
- Recent weight change
Questions to take to your appointment
- How does this factor into my overall risk score?
Build a printable questionnaire with your own results →
Where to read more
MedlinePlus, from the US National Library of Medicine, publishes patient-facing pages on individual lab tests and is a reliable next stop: medlineplus.gov/lab-tests .
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